PXD016591

PXD016591 is an original dataset announced via ProteomeXchange.

Title	Functional Analysis of the Francisella Lysine Decarboxylase
Description	Lysine decarboxylases (Ldc) are widely distributed enzymes that catalyse the decarboxylation of L-lysine to form cadaverine, a natural polyamine playing a key role in a wide range of physiological process. The Gram-negative bacterium Francisella tularensis is the etiological agent of tularemia. A previous report showed that F. novicida transposon mutant with insertions in cadA (FTT0406) which encodes a putative lysine decarboxylase (herein designed as LdcF) was attenuated in mouse spleen. Here, to address the role of this protein, we compared the proteomes of bacterial strains expressing or not LdcF.
HostingRepository	PRIDE
AnnounceDate	2021-01-14
AnnouncementXML	Submission_2021-01-14_00:00:45.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD016591
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Yohann Couté
SpeciesList	scientific name: Francisella tularensis subsp. novicida U112; NCBI TaxID: 401614;
ModificationList	Oxidation; Acetyl; Carbamidomethyl
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-12-04 05:20:05	ID requested
⏵ 1	2021-01-14 00:00:45	announced

Dataset with its publication pending

submitter keyword: Francisella tularensis, lysine decarboxylase, nanoLC-MS/MS

Virginie Brun
contact affiliation	EDyP
contact email	virginie.brun@cea.fr
lab head
Yohann Couté
contact affiliation	EDyP
contact email	yohann.coute@cea.fr
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD016591
     1. Label: PRIDE project
     2. Name: Functional Analysis of the Francisella Lysine Decarboxylase