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PXD012205

PXD012205 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleQuantitative Proteomics by SWATH-MS of Maternal Plasma Exosome Determine Pathways Associated with Term and Preterm Birth
DescriptionMaternal plasma (MP) samples were collected from group 1: term not-in labor (TNIL, n=13); group 2: term in labor (TL, n= 11), group 3: preterm premature rupture of membranes (pPROM, n=8); and group 4: preterm birth (PTB, n=13). Exosomes isolated from plasma by differential density centrifugation followed by size exclusion chromatography were characterised by morphology (electron microscopy), quantity and size (nanoparticle tracking analysis and markers (western blot). A quantitative, information-independent acquisition (Sequential Windowed Acquisition of All Theoretical Mass Spectra [SWATH]) approach was used to determine the protein profile in exosomes. Ingenuity Pathway Analysis (IPA) determined pathways associated with the protein profile identified in exosomes.
HostingRepositoryMassIVE
AnnounceDate2019-01-08
AnnouncementXMLSubmission_2019-01-08_12:26:19.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSamantha Sheller-Miller
SpeciesList scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-12-31 16:07:55ID requested
12019-01-08 12:26:20announced
Publication List
no publication
Keyword List
submitter keyword: exosome, plasma, pregnancy
Contact List
Ramkumar Menon
contact affiliationUTMB
contact emailra2menon@utmb.edu
lab head
Samantha Sheller-Miller
contact affiliationThe University of Texas Medical Branch
contact emailsashelle@utmb.edu
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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