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PXD000764

PXD000764 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDiscovery of new cerebrospinal fluid biomarkers for meningitis in children C4PR_LIV
DescriptionBacterial meningitis is usually fatal without treatment and prompt and accurate diagnosis coupled with the timely administration of parenteral antibiotics, are necessary in order to save lives. The diagnosis can sometimes be delayed whilst samples are analysed in a laboratory using traditional methods of microscopy and antigen testing. The objective of our project is to define specific protein signatures in cerebrospinal fluid associated with Streptococcus pneumoniae infection which could lead to the development of assays or point-of-care devices to improve the speed and accuracy of diagnosis, and guide the clinicians in the treatment and prognosis of children with bacterial meningitis. The associated research paper is in preparation.
HostingRepositoryPRIDE
AnnounceDate2017-10-24
AnnouncementXMLSubmission_2017-10-24_00:10:19.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD000764
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterDa Qi
SpeciesList scientific name: Streptococcus pneumoniae (strain ATCC BAA-255 / R6); NCBI TaxID: 171101; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListOxidation; Carbamidomethyl
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02014-02-18 02:11:39ID requested
12014-07-22 06:56:12announced
22014-07-25 01:53:32announcedUpdated publication reference for PubMed record(s): 25047258.
32017-02-16 00:30:23announcedUpdated project metadata.
42017-10-24 00:10:20announcedUpdated project metadata.
Publication List
Ternent T, Csordas A, Qi D, G, ó, mez-Baena G, Beynon RJ, Jones AR, Hermjakob H, Vizca, í, no JA, How to submit MS proteomics data to ProteomeXchange via the PRIDE database. Proteomics, 14(20):2233-41(2014) [pubmed]
Keyword List
curator keyword: Biomedical
submitter keyword: Meningitis, cerebrospinal fluid, Biomarkers, Streptococcus pneumoniae
Contact List
Rob Beynon
contact affiliationInstitute of Integrative Biology, University of Liverpool
contact emailR.Beynon@liverpool.ac.uk
lab head
Da Qi
contact affiliationUniversity of Liverpool
contact emailddq@liv.ac.uk
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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