⮝ Full datasets listing
PXD083520
PXD083520 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Comparative proteomic analysis of liver tissues in a mouse hepatocellular carcinoma model between the model group and the GJK high-dose group |
| Description | This study employed label-free quantitative proteomics to profile protein expression changes in liver tissues from a mouse hepatocellular carcinoma (HCC) model. A total of 6 samples were analyzed, comprising a model control group (KB, n=3) and a GJK high-dose treatment group (G, n=3). The mass spectrometry data were processed through database searching, followed by systematic bioinformatics analyses including quality control, differential protein screening, Gene Ontology (GO) annotation, KEGG pathway enrichment analysis, Gene Set Enrichment Analysis (GSEA), and protein-protein interaction (PPI) network analysis. This project aims to elucidate the molecular mechanisms underlying the therapeutic effects of GJK in hepatocellular carcinoma and to identify potential protein targets and signaling pathways involved in its anti-tumor activity. The raw mass spectrometry data and search results have been deposited to the iProX partner repository under the ProteomeXchange consortium and are associated with a concurrently submitted research manuscript. |
| HostingRepository | iProX |
| AnnounceDate | 2026-09-01 |
| AnnouncementXML | Submission_2026-09-01_20:21:13.997.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Haoyang Qin |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Astral |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-09-01 20:20:38 | ID requested | |
| ⏵ 1 | 2026-09-01 20:21:14 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Mouse hepatocellular carcinoma, Liver proteomics, Label-free quantification, GJK high-dose treatment, Differential protein expression, KEGG pathway, GO annotation, Protein-protein interaction |
Contact List
| Zhongqin Dang | |
|---|---|
| contact affiliation | Henan University of Traditional Chinese Medicine |
| contact email | dzhqn@126.com |
| lab head | |
| Haoyang Qin | |
| contact affiliation | Henan University of Traditional Chinese Medicine |
| contact email | 3194236097@qq.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
