⮝ Full datasets listing
PXD083251
PXD083251 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Essential role of Odf4 in male fertility: mediating mitochondrial function and fertilization |
| Description | Disruption of Odf4 led to male infertility by impairing mitochondrial function and fertilization capacity. Mechanistically, Lrrc71 interacted with fertilization-related proteins, including ADAM2, CALR, and ZP3R. Furthermore, Lrrc71 deficiency resulted in reduced levels of mitochondrial function-associated proteins. Collectively, our findings establish Odf4 as a central regulator of mitochondrial function and fertilization, providing mechanistic insights into the pathogenesis of infertility caused by human Odf4 mutations. |
| HostingRepository | iProX |
| AnnounceDate | 2026-08-26 |
| AnnouncementXML | Submission_2026-08-26_18:27:44.667.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Jinmei Cheng |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Exploris 240 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-08-26 18:27:27 | ID requested | |
| ⏵ 1 | 2026-08-26 18:27:45 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Odf4,mitochrondria,fertilization,male fertility |
Contact List
| Jinmei Cheng | |
|---|---|
| contact affiliation | Nantong University |
| contact email | chengjinmei@ntu.edu.cn |
| lab head | |
| Jinmei Cheng | |
| contact affiliation | Nantong University |
| contact email | chengjinmei@ntu.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
