⮝ Full datasets listing
PXD083126
PXD083126 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Amyloid Subtyping from FFPE Biopsies |
| Description | This dataset contains mass spectrometry-based proteomics data generated for the clinical identification and subtyping of amyloid deposits from formalin-fixed, paraffin-embedded (FFPE) tissue biopsies. The study evaluates a rapid sample preparation workflow coupled with high-flow liquid chromatography–tandem mass spectrometry (LC-MS/MS) for the characterization of amyloid-associated proteins. FFPE tissue sections were processed using Congo red staining and targeted microdissection of amyloid-positive regions. Proteins were extracted using a heat-assisted extraction procedure followed by rapid tryptic digestion. The resulting peptide mixtures were analyzed using high-flow liquid chromatography coupled to a Q Exactive Orbitrap mass spectrometer operated in data-dependent acquisition mode. The dataset includes representative proteomic data generated from clinical amyloid tissue specimens. Protein identification and characterization were performed based on peptide-spectrum matches, unique peptide identification, |
| HostingRepository | iProX |
| AnnounceDate | 2026-08-22 |
| AnnouncementXML | Submission_2026-08-25_02:16:58.865.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Naga Veera Yerra |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-08-25 02:16:38 | ID requested | |
| ⏵ 1 | 2026-08-25 02:16:59 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Amyloidosis, amyloid subtyping, FFPE tissue, clinical proteomics, LC-MS/MS, mass spectrometry, Q Exactive Orbitrap, high-flow liquid chromatography, Congo red, protein identification,amyloid-associated proteins |
Contact List
| Naga Veera Yerra | |
|---|---|
| contact affiliation | The Mount Sinai Hospital |
| contact email | nagaveeray@gmail.com |
| lab head | |
| Naga Veera Yerra | |
| contact affiliation | The Mount Sinai Hospital |
| contact email | nagaveeray@gmail.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
