PXD082858

PXD082858 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Trypanosoma cruzi trypomastigote proteins in VPS23 hemiknockout
Description	We have analysed the protein composition of wild-type, a T7Cas9 strain used generate CRISPR/Cas9 deletion of VPS23 gene in Trypanosoma cruzi. The main objective was to compare the quantitative changes observed in a clone that only one copy of the gene was replaced with the parental parasite line used to make the deletion. The obtained clone presented several phenotypes both related to cell infection in vitro and animal progression of the disease.
HostingRepository	PRIDE
AnnounceDate	2026-09-05
AnnouncementXML	Submission_2026-09-05_06:08:32.551.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sergio Schenkman
SpeciesList	scientific name: Trypanosoma cruzi Dm28c; NCBI TaxID: NEWT:1416333;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2026-08-19 13:21:46	ID requested
⏵ 1	2026-09-05 06:08:33	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: knockout, trypomastigotes, VPS23,Trypanosoma cruzi

submitter keyword: knockout, trypomastigotes, VPS23,Trypanosoma cruzi

Contact List

Sergio Schenkman
contact affiliation	Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil
contact email	sschenkman@unifesp.br
lab head
Sergio Schenkman
contact affiliation	Universidade Federal de São Paulo
contact email	sschenkman@unifesp.br
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD082858
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD082858

PRIDE project URI

Repository Record List

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