⮝ Full datasets listing
PXD082578
PXD082578 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Organelle-specific protein alteration |
| Description | Current proteomics research on drug mechanisms primarily focuses on whole-cell studies, which are inadequate for effectively analyzing the dynamic molecular networks and mechanisms between organelles. This study, utilizing organelle proteomics analysis after treating cells with 30 different clinical drugs, uncovering different durgs induced quiet different changes in organelle protein abundance. It also reveals extensive protein translocation between organelles, a phenomenon that is nearly undetectable at the whole-cell level. Additionally, the study highlights significant differences in the interaction relationships of the same protein complexes within different organelles. |
| HostingRepository | iProX |
| AnnounceDate | 2026-08-14 |
| AnnouncementXML | Submission_2026-08-14_02:06:40.110.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Zhixiang Yan |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | ZenoTOF 7600 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-08-14 02:05:32 | ID requested | |
| ⏵ 1 | 2026-08-14 02:06:40 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: organelle proteomics |
Contact List
| Zhixiang Yan | |
|---|---|
| contact affiliation | Sun Yat-sen University |
| contact email | yanzhx3@mail.sysu.edu.cn |
| lab head | |
| Zhixiang Yan | |
| contact affiliation | Sun Yat-sen University |
| contact email | yanzhx3@mail.sysu.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
