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PXD082501

PXD082501 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCardiac amyloidosis typing by S-Trap-based protocol and intensity-based diagnostic algorithm
DescriptionProposal of an S-Trap-based proteomics workflow for amyloid typing of EMBs coupled with a scoring algorithm based on protein intensities.The protocol and the algorithm have been validated by the comparison of MS-based diagnosis with immunohistochemistry diagnosis and patient clinical data. The study was conducted on 28 patients with a clinical diagnosis of CA and either an inconclusive IHC response or an atypical disease phenotype, that were selected for additional proteomics-based investigation.
HostingRepositoryPRIDE
AnnounceDate2026-08-18
AnnouncementXMLSubmission_2026-08-18_02:07:07.879.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterFrancesco Greco
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-08-13 10:20:07ID requested
12026-08-18 02:07:08announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: diagnostic algorithm, laser-capture microdissection,cardiac amyloidosis, microproteomics, typing software
Contact List
Liam A. McDonnell
contact affiliationFondazione Pisana per la Scienza ETS
contact emailliam@fpscience.it
lab head
Francesco Greco
contact affiliationFondazione Toscana Gabriele Monasterio
contact emailf.greco@fpscience.it
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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