⮝ Full datasets listing
PXD082253
PXD082253 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Intestinal β-galactosidase affects host health by regulating flavonoid metabolism |
| Description | Untargeted metabolomic analysis was performed to identify the principal aglycone generated by the engineered Escherichia coli Nissle 1917 strain expressing β-galactosidase (EcN-bgal). Culture supernatants from EcN-bgal and the vector control strain were collected and subjected to LC–MS-based metabolomic profiling. Comparative analysis revealed substantial alterations in the metabolite composition of the EcN-bgal supernatant, enabling the identification of β-galactosidase-dependent metabolites and the characterization of the major aglycone produced by the engineered strain. |
| HostingRepository | iProX |
| AnnounceDate | 2026-08-05 |
| AnnouncementXML | Submission_2026-08-06_00:56:50.004.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Kaixin Ding |
| SpeciesList | scientific name: Escherichia coli Nissle 1917; NCBI TaxID: 316435; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-08-06 00:56:19 | ID requested | |
| ⏵ 1 | 2026-08-06 00:56:50 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Untargeted metabolomics, LC–MS, Escherichia coli Nissle 1917, EcN-bgal, β-galactosidase |
Contact List
| Shenhai Gong | |
|---|---|
| contact affiliation | Southern Medical University |
| contact email | gsh0526@smu.edu.cn |
| lab head | |
| Kaixin Ding | |
| contact affiliation | Southern Medical University |
| contact email | dingkaixin97@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
