PXD082132

PXD082132 is an original dataset announced via ProteomeXchange.

Title	Quantitative proteomic profiling of DDX20 knockdown versus control groups in human 293T cells and mouse C18-4 spermatogonial cells
Description	We performed label-free quantitative proteomics to investigate global protein expression changes upon DDX20 knockdown. Two cell models were included: human HEK293T cells and mouse C18-4 spermatogonial progenitor cells. Each cell line contains DDX20 knockdown group and negative control group to explore conserved and cell-type-specific proteomic alterations regulated by DDX20.
HostingRepository	iProX
AnnounceDate	2026-08-04
AnnouncementXML	Submission_2026-08-04_00:43:19.627.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Dingfeng Zou
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606; scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	4800 Plus MALDI TOF/TOF

Revision	Datetime	Status	ChangeLog Entry
0	2026-08-04 00:42:50	ID requested
⏵ 1	2026-08-04 00:43:20	announced

Dataset with its publication pending

submitter keyword: DDX20, quantitative proteomics, 293T cell, C18-4 cell, spermatogonia, gene knockdown, mass spectrometry, differential proteome

Wei Song
contact affiliation	Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College
contact email	songwei@ibms.pumc.edu.cn
lab head
Dingfeng Zou
contact affiliation	Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College
contact email	dfmufu@163.com
dataset submitter

iProX dataset URI