⮝ Full datasets listing
PXD082107
PXD082107 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic profiling of senescent tumor cell membrane |
| Description | Senescent tumor cells exhibit intrinsically enhanced immunogenicity and can spontaneously generate tumor neoantigens. This endows their cell membrane with considerable potential as a versatile drug delivery platform and a reservoir of tumor-specific antigens for cancer immunotherapy and vaccine development. To explore the immune potential of senescent tumor cells, 4T1 breast cancer cells were subjected to a senescence inducer, doxorubicin to establish a stable senescent model. To systematically dissect the functional disparities between tumor cell membrane and senescent tumor cell membrane, label-free quantitative membrane proteomic analysis was performed on these two types of membrane vesicles. |
| HostingRepository | iProX |
| AnnounceDate | 2026-08-03 |
| AnnouncementXML | Submission_2026-08-03_18:02:28.853.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Qin Fan |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Astral |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-08-03 18:02:10 | ID requested | |
| ⏵ 1 | 2026-08-03 18:02:29 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Tumor immunotherapy |
Contact List
| Sheng Wang | |
|---|---|
| contact affiliation | Tianjin University |
| contact email | shengwang@tju.edu.cn |
| lab head | |
| Qin Fan | |
| contact affiliation | Tianjin University |
| contact email | fanqin@tju.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
