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PXD082067

PXD082067 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic identification of DNAJC5-interacting proteins via immunoprecipitation-mass spectrometry (IP-MS) in ovarian cancer cells
DescriptionOvarian cancer is a lethal gynecological malignancy with poorly understood molecular mechanisms. DNAJC5 has been identified as a potential driver of lipogenic tumor metabolism; however, its interacting protein partners remain largely unknown. To elucidate the molecular basis of DNAJC5 function, we performed immunoprecipitation-mass spectrometry (IP-MS) using anti-DNAJC5 antibody in SK-OV-3 ovarian cancer cells. The raw mass spectrometry data (.RAW) and the accompanying search engine output files (including Proteins, PSMs, and PeptideGroups) are presented here. This dataset aims to provide comprehensive evidence for the identification of DNAJC5-interacting proteins, thereby contributing to our understanding of its role in ovarian cancer progression. The data are available for review and will support future mechanistic and therapeutic studies.
HostingRepositoryiProX
AnnounceDate2026-08-03
AnnouncementXMLSubmission_2026-08-12_19:35:12.902.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJuan Zhang
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-08-03 00:40:49ID requested
12026-08-12 19:35:13announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: DNAJC5, TAF15, Immunoprecipitation-mass spectrometry (IP-MS), Protein-protein interaction, Ovarian cancer, SK-OV-3, Proteomics
Contact List
Juan Zhang
contact affiliationDepartment of Obstetrics and Gynecology, Zhongnan Hospital of Wuhan University
contact emailzn003075@whu.edu.cn
lab head
Juan Zhang
contact affiliationDepartment of Obstetrics and Gynecology, Zhongnan Hospital of Wuhan University
contact emailzn003075@whu.edu.cn
dataset submitter
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iProX dataset URI