PXD081500 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Multi-species genome-wide CRISPR screens identify conserved suppressors of cold-induced cell death |
| Description | Quantitative tandem-mass-tag (TMT10-plex) proteomic profiling of hamster BHK-21 cells maintained at 37 °C versus cells exposed to 4 °C (four replicates per condition). Peptides were fractionated by offline high-pH reversed-phase chromatography and analyzed on a Thermo Orbitrap Eclipse. This dataset accompanies a study of the cellular response to prolonged cold, and is paired with RNA-seq data |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-09-10 |
| AnnouncementXML | Submission_2026-09-09_16:59:23.136.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Tara Thakurta |
| SpeciesList | scientific name: Mesocricetus auratus (Golden hamster); NCBI TaxID: NEWT:10036; |
| ModificationList | TMT6plex-126 reporter+balance reagent acylated residue; phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Orbitrap Eclipse |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-07-22 14:53:35 | ID requested | |
| ⏵ 1 | 2026-09-09 16:59:23 | announced | |
Publication List
Keyword List
| submitter keyword: Mesocricetus auratus, hypothermia, TMT, Orbitrap Eclipse, cold exposure, quantitative proteomics,BHK-21 |
Contact List
| Siniša Hrvatin |
|---|
| contact affiliation | Whitehead Institute, MIT, & HHMI |
| contact email | shrvatin@wi.mit.edu |
| lab head | |
| Tara Thakurta |
|---|
| contact affiliation | Whitehead Institute |
| contact email | taragt@wi.mit.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD081500 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD081500
- Label: PRIDE project
- Name: Multi-species genome-wide CRISPR screens identify conserved suppressors of cold-induced cell death
