PXD080805 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Paleoproteomics data of teeth analysis |
| Description | The estimation of the biological sex of archeological remains is crucial information in bioarchaeology and forensic anthropology. In recent years, proteomics based on molecular sexual dimorphism have emerged as a preferred method, particularly because of its minimally-invasive approach to extracting amelogenin X and Y proteins from tooth enamel. However, there is an increasing demand to accelerate this process while facilitating the analysis of large archaeological assemblages. This study presents a novel high-throughput targeted paleoproteomics method for biological sex estimation using MALDI-CASI-FTICR mass spectrometry. This approach combines the strengths of existing methods, including ultra-high resolution, significantly reduced processing times, targeted analysis, and scalability to large archaeological sample sets. The method was initially validated on modern individuals with known sex and subsequently applied to 130 adult and juvenile individuals from medieval Great Moravia (present-day Czech Republic). Biological sex was successfully estimated for all but one of the individuals. The results not only provide a more efficient biological sex estimation but also help to resolve a few errors in sex assessment previously encountered with osteomorphological and tooth morphometric techniques. The implementation of this method significantly improves the accuracy and efficiency of biological sex estimation, offering a powerful tool for anthropological research. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-09-02 |
| AnnouncementXML | Submission_2026-09-02_03:02:45.464.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | BRAY FABRICE |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | phosphorylated residue; monohydroxylated residue; deamidated residue |
| Instrument | Q Exactive Plus |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-07-09 08:22:26 | ID requested | |
| ⏵ 1 | 2026-09-02 03:02:46 | announced | |
Publication List
Keyword List
| submitter keyword: sex estimation,Paleoproteomics, teeh |
Contact List
| fabrice bray |
|---|
| contact affiliation | IMEC UAR 2638 France Villeneuve d'ascq |
| contact email | fabrice.bray@univ-lille.fr |
| lab head | |
| BRAY FABRICE |
|---|
| contact affiliation | MSAP USR 3290 |
| contact email | fabrice.bray@univ-lille.fr |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD080805 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD080805
- Label: PRIDE project
- Name: Paleoproteomics data of teeth analysis
