PXD080789

PXD080789 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Q-TOF/MS detected results of the Lysostaphin and recombinant Lysostaphin-ELP(V)90
Description	This study engineered a recombinant lysostaphin (Lst) variant, Lst-ELP(V)₉₀, as a therapeutic candidate for prosthetic explant biofilm infections caused by methicillin-resistant Staphylococcus aureus (MRSA). Compared with the wild-type (WT) lysostaphin, the recombinant construct exhibited markedly improved stability and attenuated immunogenicity, establishing a robust foundation for downstream drug development.
HostingRepository	PRIDE
AnnounceDate	2026-08-20
AnnouncementXML	Submission_2026-08-19_22:38:27.982.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Guoqing Fan
SpeciesList	scientific name: Escherichia coli; NCBI TaxID: NEWT:562;
ModificationList	No PTMs are included in the dataset
Instrument	Q-Tof Ultima

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2026-07-09 02:01:03	ID requested
⏵ 1	2026-08-19 22:38:28	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: lysostaphin, ELP,MRSA, Q/TOF/MS, biofilm

submitter keyword: lysostaphin, ELP,MRSA, Q/TOF/MS, biofilm

Contact List

Weiping Gao
contact affiliation	Beijing Advanced Center of Cellular Homeostasis and Aging-Related Diseases, Department of Biomedical Engineering, Institute of Advanced Clinical Medicine, Peking University, Beijing 100191, China
contact email	gaoweiping@hsc.pku.edu.cn
lab head
Guoqing Fan
contact affiliation	Peking University
contact email	fgq_pku@hsc.pku.edu.cn
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/08/PXD080789
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/08/PXD080789

PRIDE project URI

Repository Record List

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