PXD080702

PXD080702 is an original dataset announced via ProteomeXchange.

Title	Coffee remodels the histone acetylation landscape in association with suppression of the MYC transcriptional program
Description	This dataset contains data-independent acquisition (DIA) proteomics data generated from K562 human leukemia cells treated with coffee extract or vehicle control. Quantitative proteomic analysis was performed to investigate molecular mechanisms underlying coffee-induced epigenetic remodeling. The proteomics dataset was integrated with histone modification profiling, ChIP-seq and RNA-seq analyses to characterize pathways associated with histone acetylation and MYC transcriptional regulation.
HostingRepository	jPOST
AnnounceDate	2026-07-08
AnnouncementXML	Submission_2026-07-07_23:30:07.484.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kazumasa Aoyama
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	unknown modification; N6-biotinyl-L-lysine
Instrument	instrument

Revision	Datetime	Status	ChangeLog Entry
0	2026-07-07 23:30:04	ID requested
⏵ 1	2026-07-07 23:30:07	announced

Dataset with its publication pending

submitter keyword: Coffee, histone acetylation, H3K27ac, MYC, DIA proteomics, K562

Kazumasa Aoyama
lab head
Kazumasa Aoyama
contact affiliation	Division of Hygienic Chemistry, Faculty of Pharmacy, Keio University
dataset submitter

jPOST dataset URI

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