PXD080671

PXD080671 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	HDX-MS analysis of binding interfaces on ARMH3 in the presence of Arl5b(GTPyS) and GBF1
Description	We carried out 4 HDX-MS experiments to investigate the ARMH3 interactions with PI4Kb, Arl5b(GTPyS) and GBF1 (ARMH3+Arl5b, ARMH3+GBF1(1-709)) and ARMH3+GBF1(364-395)). Analysis of these four experiments defined the Arl5b intereface on ARMH3 and defined the disordered linker region located in the DCB-HUS domains region of GBF1 (residues 364-395) as the ARMH3 binding region (ABR)
HostingRepository	PRIDE
AnnounceDate	2026-09-07
AnnouncementXML	Submission_2026-09-07_04:22:36.680.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	John Burke
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 120; impact II

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2026-07-07 02:53:52	ID requested
⏵ 1	2026-09-07 04:22:37	announced

Publication List

Scott MK, Klynsoon GCT, Walsh EE, Suresh S, Nyvall HG, Burke JE, ARMH3 acts as a central scaffold at the Golgi/TGN through interactions with Arl5, GBF1, and PI4KB. J Biol Chem, 302(8):113307(2026) [pubmed]
10.1016/j.jbc.2026.113307;

Scott MK, Klynsoon GCT, Walsh EE, Suresh S, Nyvall HG, Burke JE, ARMH3 acts as a central scaffold at the Golgi/TGN through interactions with Arl5, GBF1, and PI4KB. J Biol Chem, 302(8):113307(2026) [pubmed]

10.1016/j.jbc.2026.113307;

Keyword List

submitter keyword: ARMH3, GBF1,HDX-MS. PI4Kb

submitter keyword: ARMH3, GBF1,HDX-MS. PI4Kb

Contact List

Dr. John Burke
contact affiliation	University of Victoria
contact email	jeburke@uvic.ca
lab head
John Burke
contact affiliation	University of Victoria
contact email	jeburke@uvic.ca
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD080671
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD080671

PRIDE project URI

Repository Record List

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