PXD080632

PXD080632 is an original dataset announced via ProteomeXchange.

Title	timsTOF DDA Dataset for Article “False discovery rate control enables trustworthy AI-based de novo peptide sequencing”
Description	This project contains an in-house timsTOF DDA proteomics dataset used in the study "False discovery rate control enables trustworthy AI-based de novo peptide sequencing". The dataset includes 100 HEK293T samples and 100 mouse tissue samples acquired for routine quality control on a timsTOF mass spectrometer. Human and mouse samples were searched with PEAKS Online version 12 and identifications were filtered at 1% FDR, yielding 32,018,308 PSMs. Carbamidomethylation of cysteine was used as a fixed modification and oxidation of methionine was used as a variable modification.
HostingRepository	iProX
AnnounceDate	2026-07-06
AnnouncementXML	Submission_2026-07-06_18:51:59.021.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zhendong Liang
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606; scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2026-07-06 18:49:52	ID requested
⏵ 1	2026-07-06 18:51:59	announced

Dataset with its publication pending

submitter keyword: timsTOF, DDA, de novo peptide sequencing, FDR control, CCT, π-NovoQC, HEK293T, mouse tissue, PEAKS Online

Cheng Chang
contact affiliation	National Center for Protein Sciences (Beijing)
contact email	changcheng@ncpsb.org.cn
lab head
Zhendong Liang
contact affiliation	Tsinghua University, Peng Cheng Laboratory
contact email	zhendongliang040@gmail.com
dataset submitter

iProX dataset URI