PXD080591 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Integrated transcriptomic and proteomic analysis reveals Runx2b-associated molecular regulation of intermuscular bone development in Culter alburnus |
| Description | This dataset contains LC-MS/MS-based proteomic data generated from muscle/myoseptal tissues of wild-type, heterozygous runx2b mutant, and homozygous runx2b mutant Culter alburnus individuals. The study aimed to characterize proteomic changes associated with runx2b-mediated intermuscular bone reduction and loss. Three biological replicates were analyzed for each genotype group. Differential protein abundance analysis and integrated transcriptomic-proteomic analysis were used to identify candidate proteins and functional modules associated with extracellular matrix remodeling, cytoskeletal organization, calcium signaling, muscle contraction, and osteogenic regulation during intermuscular bone development. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-09-07 |
| AnnouncementXML | Submission_2026-09-07_04:22:23.976.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Xiaohui Xu |
| SpeciesList | scientific name: Culter alburnus; NCBI TaxID: NEWT:194366; |
| ModificationList | iodoacetamide derivatized residue |
| Instrument | Orbitrap Astral |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-07-06 06:22:33 | ID requested | |
| ⏵ 1 | 2026-09-07 04:22:24 | announced | |
Publication List
Keyword List
| submitter keyword: Culter alburnus |
| intermuscular bone |
| runx2b |
| proteomics |
| DIA |
| LC-MS/MS |
| gene editing |
| skeletal development |
| muscle/myoseptal tissue |
Contact List
| Jianbo Zheng |
|---|
| contact affiliation | Affiliation* Key Laboratory of Genetics and Breeding, Zhejiang Institute of Freshwater Fisheries, Huzhou, China |
| contact email | 21207054@zju.edu.cn |
| lab head | |
| Xiaohui Xu |
|---|
| contact affiliation | Yangtze Delta Region Institute of Tsinghua University Zhejiang |
| contact email | xiaohuixu71@outlook.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD080591 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD080591
- Label: PRIDE project
- Name: Integrated transcriptomic and proteomic analysis reveals Runx2b-associated molecular regulation of intermuscular bone development in Culter alburnus
