⮝ Full datasets listing
PXD080589
PXD080589 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Characterization of the Aggregate Proteome in Alzheimers Disease with Psychosis |
| Description | Insoluble brain fractions of human patients with Alzheimers disease or Alzheimers plus characteristics of psychosis and matched controls were collected in standard laemmli buffer and heated at 95C for 5 minutes in 10mM DTT. Approximately 100 micrograms of each sample were loaded into STrap micro columns following vendor protocols and digested with Trypsin overnight at room temperature. The resulting peptide digest was measured by peptide colorimetric assay and 4ng was loaded onto EvoTips for diaPASEF analysis on a TIMSTOF Ultra2 system using a 40SPD nanoflow gradient. The resulting files were analyzed in SpectroNaut 21. |
| HostingRepository | MassIVE |
| AnnounceDate | 2026-07-06 |
| AnnouncementXML | Submission_2026-07-06_07:48:18.434.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | ben orsburn |
| SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
| ModificationList | Oxidation; GG |
| Instrument | timsTOF Ultra 2 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-07-06 06:01:52 | ID requested | |
| ⏵ 1 | 2026-07-06 07:48:18 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: Psychosis, Protein insolubility, Alzheimer, DatasetType:Proteomics |
Contact List
| Ben Orsburn | |
|---|---|
| contact affiliation | University of Pittsburgh |
| contact email | orsburn@pitt.edu |
| lab head | |
| ben orsburn | |
| contact affiliation | The University of Pittsburgh |
| contact email | ben_orsburn3@hotmail.com |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v13/MSV000102374/ |
