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PXD080533

PXD080533 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleImmunoprecipitation-mass spectrometry (IP-MS) reveals the PLIN2 interactome and its disruption by O-GlcNAcylation in MASH
DescriptionMetabolic dysfunction-associated steatohepatitis (MASH) is driven by hepatocellular lipid overload and altered inter-organelle crosstalk. To elucidate the molecular mechanisms by which Perilipin 2 (PLIN2) regulates lipid droplet (LD)-mitochondria tethering, and to determine how this is affected by its O-GlcNAcylation under lipotoxic stress, we performed immunoprecipitation coupled with mass spectrometry (IP-MS)
HostingRepositoryiProX
AnnounceDate2026-07-03
AnnouncementXMLSubmission_2026-07-03_02:43:44.080.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterXin Tang
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-07-03 02:42:36ID requested
12026-07-03 02:43:44announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: IP-MS, Interactome, PLIN2, O-GlcNAcylation
Contact List
Ni Tang
contact affiliationChongqing Medical University
contact emailnitang@cqmu.edu.cn
lab head
Xin Tang
contact affiliationChongqing Medical University
contact email1132415821@qq.com
dataset submitter
Full Dataset Link List
iProX dataset URI