⮝ Full datasets listing
PXD080462
PXD080462 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Dual GIP/GLP-1 receptor agonist tirzepatide ameliorates adipose tissue inflammation in high-fat, high-fructose diet-induced obese mice via the IL-17A/IL-17RA axis |
| Description | This study aimed to investigate the effects of the glucose-dependent insulinotropic polypeptide/glucagon-like peptide-1 dual-receptor agonist tirzepatide (TZP) on epididymal white adipose tissue (eWAT) inflammation in high-fat/high-fructose (HFHFr) diet–induced obese mice and to elucidate the underlying mechanisms. In addition, the anti-inflammatory effects of TZP were compared with those of the GLP-1 receptor agonist semaglutide (Sema). |
| HostingRepository | iProX |
| AnnounceDate | 2026-07-02 |
| AnnouncementXML | Submission_2026-07-01_19:57:00.689.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Fanfan Song |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-07-01 19:56:08 | ID requested | |
| ⏵ 1 | 2026-07-01 19:57:01 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: tirzepatide, semaglutide, IL-17A–IL-17RA axis, adipose tissue inflammation, macrophage polarization |
Contact List
| Luping Ren | |
|---|---|
| contact affiliation | Hebei General Hospital |
| contact email | renluping1122@163.com |
| lab head | |
| Fanfan Song | |
| contact affiliation | Hebei General Hospital |
| contact email | songff1995@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
