PXD080417

PXD080417 is an original dataset announced via ProteomeXchange.

Title	Brain tissue-derived exosomal proteomics after traumatic brain injury in rats
Description	Traumatic brain injury (TBI) induces complex secondary pathological processes, including neuroinflammation and intercellular communication within the injured brain microenvironment. Brain tissue-derived exosomes may provide information on local molecular alterations after injury, but their protein cargo changes after TBI remain incompletely characterized. In this project, brain tissue-derived exosomes were isolated from rats subjected to TBI or sham surgery and analyzed using label-free LC-MS/MS proteomics. The dataset includes five TBI samples and five sham control samples and was generated to identify injury-associated changes in exosomal protein cargo and provide a resource for exploring exosome-related molecular alterations during secondary brain injury.
HostingRepository	iProX
AnnounceDate	2026-07-01
AnnouncementXML	Submission_2026-08-13_19:59:54.614.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yibin Liu
SpeciesList	scientific name: Rattus norvegicus; NCBI TaxID: 10116;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2026-07-01 02:18:04	ID requested
⏵ 1	2026-08-13 19:59:55	announced

Dataset with its publication pending

submitter keyword: traumatic brain injury, exosomes, extracellular vesicles, proteomics

Yibin Liu
contact affiliation	The Second Affiliated Hospital of Fujian Medical University
contact email	liuyb052107@163.com
lab head
Yibin Liu
contact affiliation	The Second Affiliated Hospital of Fujian Medical University
contact email	liuyb052107@163.com
dataset submitter

iProX dataset URI