⮝ Full datasets listing
PXD080297
PXD080297 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Mechanical Pressure-Induced Proteome Remodeling in Corneal Epithelial Cells |
| Description | Mechanical pressure can substantially alter the mechano-microenvironment of corneal epithelial cells and activate the mechanosensitive channel Piezo1 as well as its downstream interacting proteins. In this study, we will perform immunoprecipitation using an anti-Piezo1 antibody, coupled with mass spectrometry analysis (IP-MS), to systematically identify the differential interactome of Piezo1 in corneal epithelial cells under pressure stimulation, with the aim of revealing the key molecular mechanisms underlying mechanotransduction. |
| HostingRepository | iProX |
| AnnounceDate | 2026-06-27 |
| AnnouncementXML | Submission_2026-06-29_01:57:01.172.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Miaomiao Chi |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Astral |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-06-29 01:56:40 | ID requested | |
| ⏵ 1 | 2026-06-29 01:57:01 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: corneal epithelium, mechanical pressure |
Contact List
| Jing Hong | |
|---|---|
| contact affiliation | Peking University Third Hospital |
| contact email | hongjing196401@163.com |
| lab head | |
| Miaomiao Chi | |
| contact affiliation | Peking University Third Hospital |
| contact email | miaoc001@126.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
