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PXD080097

PXD080097 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDiscovery and validation of plasma-based protein biomarkers for the aetiological distinction of bacterial and non-bacterial febrile infections in African children
DescriptionIn many low resource settings, the clinical management of children with febrile infections is hindered by poor access to diagnostic tools to determine whether the cause of an infection is bacterial, viral or parasitic. As a result, many clinicians resort to the default prescription of antibiotics as a safety precaution, contributing to the alarming spread of antimicrobial resistance. Commonly used biomarkers for identification of bacterial sepsis such as CRP lack aetiological specificity and are frequently elevated by non-bacterial infections including malaria. We set out to discover and validate new biomarkers for the characterization of the microbial aetiology of febrile acute infections in Kenyan children.
HostingRepositoryMassIVE
AnnounceDate2026-06-26
AnnouncementXMLSubmission_2026-06-26_14:06:09.019.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterElisha Omer
SpeciesList scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-06-23 23:13:13ID requested
12026-06-26 14:06:09announced
Publication List
no publication
Keyword List
submitter keyword: febrile infections, biomarkers, discover, validate, aetiology, DatasetType:Proteomics
Contact List
Prof. Charles J. Sande
contact affiliationKEMRI-Wellcome Trust Research Programme, Kilifi
contact emailcsande@kemri-wellcome.org
lab head
Elisha Omer
contact affiliationKEMRI-Wellcome Trust
contact emaileomer@kemri-wellcome.org
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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