⮝ Full datasets listing
PXD080089
PXD080089 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Benzyl alcohol biosynthesis and its subcellular compartmentalization: from scent formation to salicylic acid production |
| Description | Benzyl alcohol, a simple aromatic alcohol found in more than half of seed plants, plays important roles in plant-environmental interactions and serves as a precursor of benzyl benzoate, an intermediate in the phenylalanine-dependent salicylic acid biosynthesis. Despite its importance, the enzyme responsible for its formation in plants has remained unknown. Here, using a combination of classical biochemical, proteomic and genetic approaches, we demonstrated that two NADPH-dependent benzaldehyde reductases, differing by only three amino acids, are responsible for the formation of benzyl alcohol and its downstream derivatives, benzyl benzoate and methyl salicylate, in petunia flowers. Analysis of salicylic acid levels in petunia stems upon pathogen infection revealed that downregulation of benzaldehyde reductase expression substantially reduces salicylic acid levels. These findings provide direct evidence that benzaldehyde reductase represents the last missing enzyme in salicylic acid biosynthesis via the benzyl benzoate intermediate. Moreover, the subcellular localization of benzaldehyde reductase homologs across flowering plants is species-specific, occurring either in peroxisomes or cytosol, suggesting that different species employ distinct compartmental organization for phenylalanine-dependent salicylic acid biosynthesis. |
| HostingRepository | jPOST |
| AnnounceDate | 2026-06-23 |
| AnnouncementXML | Submission_2026-06-23_19:06:48.187.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yi-Kai Liu |
| SpeciesList | scientific name: cellular organisms; NCBI TaxID: 131567; |
| ModificationList | S-carboxamidomethyl-L-cysteine; alpha-amino acetylated residue; L-methionine sulfoxide |
| Instrument | instrument |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-06-23 19:06:19 | ID requested | |
| ⏵ 1 | 2026-06-23 19:06:48 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Benzyl alcohol, benzaldehyde reductase, petunia, salicylic acid, subcellular compartmentalization |
Contact List
| Dr. Natalia Dudareva | |
|---|---|
| lab head | |
| Yi-Kai Liu | |
| contact affiliation | Purdue University |
| dataset submitter | |
Full Dataset Link List
| jPOST dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST004721/ |
