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PXD079929

PXD079929 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleQuantitative serum proteomics of monogamous deer mice (Peromyscus) reveals systemic alterations driven by pair-bonding and bond disruption
DescriptionThis dataset contains TMT-10plex quantitative proteomics of serum isolated from monogamous deer mice (Peromyscus). The study investigates the systemic physiological impact of social interactions, specifically comparing pair-bonded animals to those that have experienced bond disruption. The circulating serum proteome was analyzed to identify factors that mediate peripheral tissue responses to social history. This serum data supports findings regarding the impact of social bonds on the lung transcriptome (Naderi et al., 2023, BMC Genomics) and systemic transcriptomic stochasticity/gene canalization in cultured cells.
HostingRepositoryPRIDE
AnnounceDate2026-06-23
AnnouncementXMLSubmission_2026-06-23_11:05:55.135.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterKim-Tuyen Huynh-Dam
SpeciesList scientific name: Peromyscus; NCBI TaxID: NEWT:10040;
ModificationListTMT6plex-126 reporter+balance reagent acylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-06-19 11:51:25ID requested
12026-06-23 11:05:56announced
Publication List
Naderi A, Liles K, Burns T, Chavez B, Huynh-Dam KT, Kiaris H, Pair bonding and disruption impact lung transcriptome in monogamous Peromyscus californicus. BMC Genomics, 24(1):789(2023) [pubmed]
10.1186/s12864-023-09873-6;
Keyword List
submitter keyword: deer mouse, social stress, bond disruption, pair-bonding, TMT-10plex,Peromyscus, serum, circulating liquidome, gene canalization
Contact List
Hippokratis Kiaris
contact affiliationThe Department of Drug Discovery and Biomedical Sciences, College of Pharmacy, University of South Carolina
contact emailKIARISH@cop.sc.edu
lab head
Kim-Tuyen Huynh-Dam
contact affiliationUniversity of South Carolina
contact emailkimtuyenhuynhdam@gmail.com
dataset submitter
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Dataset FTP location
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PRIDE project URI
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