⮝ Full datasets listing
PXD079863
PXD079863 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Data-independent acquisition (DIA) proteomics sequencing of tMCAO rat brain |
| Description | To investigate the role of the Jak2/Stat3 pathway in acute cerebral ischemia-reperfusion injury (CIRI), we employed AAV9-mediated gene silencing in a tMCAO rat model. Specifically, AAV9-shNC (control) or AAV9-shJak2 (knockdown) was administered, and analyses were performed at 2 days post-surgery. To further identify downstream targets of Jak2/Stat3 signaling under tMCAO conditions, we conducted DIA proteomics sequencing to compare protein expression profiles between tMCAO+shNC and tMCAO+shJak2 rats. |
| HostingRepository | iProX |
| AnnounceDate | 2026-06-18 |
| AnnouncementXML | Submission_2026-06-18_01:10:19.071.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Gangfang Xu |
| SpeciesList | scientific name: Rattus norvegicus; NCBI TaxID: 10116; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF HT |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-06-18 01:09:06 | ID requested | |
| ⏵ 1 | 2026-06-18 01:10:19 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Data-independent acquisition (DIA) proteomics sequencin |
| tMCAO |
| Jak2 |
| cerebral ischemia-reperfusion injury (CIRI) |
Contact List
| Haitong Wan | |
|---|---|
| contact affiliation | Zhejiang Chinese Medical University |
| contact email | whtong@126.com |
| lab head | |
| Gangfang Xu | |
| contact affiliation | Zhejiang Chinese Medical University |
| contact email | guanfengxu@126.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
