PXD079740

PXD079740 is an original dataset announced via ProteomeXchange.

Title	Quercetagetin-rich flavonoids (QG-MF) from marigold induce apoptosis via activating p53/p21 pathway in non-small cell lung cancer cells
Description	Label-free quantitative proteomics was applied to screen differentially expressed proteins in QG-MF-treated A549 lung cancer cells. Functional enrichment analysis and in vitro/in vivo validation confirmed the regulation of the p53/p21 signaling cascade. All mass spectrometry raw data and processed analytical files are deposited in compliance with MIAPE guidelines for ProteomeXchange.
HostingRepository	iProX
AnnounceDate	2026-06-15
AnnouncementXML	Submission_2026-07-31_01:41:55.030.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Limin Wang
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2026-06-15 17:58:28	ID requested
⏵ 1	2026-07-31 01:41:55	announced

Dong Z, Cheng X, Lian Y, Wu D, Liu K, Feng X, Xue Q, Chen Q, Wang L, Quercetagetin-rich flavonoids from marigold induce apoptosis inhibit metastasis of non-small cell lung cancer via the p53/p21 signaling pathway. Front Oncol, 16():1813351(2026) [pubmed]

submitter keyword: apoptosis, metastasis, NSCLC, p53/p21 signaling pathway, QG-MF, Tagetes erecta L.

Limin Wang
contact affiliation	Hebei University of Engineering
contact email	wanglimin@hebeu.edu.cn
lab head
Limin Wang
contact affiliation	Hebei University of Engineering
contact email	wanglimin@hebeu.edu.cn
dataset submitter

iProX dataset URI