PXD079423 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Adaptation of white adipocytes to cooler temperatures: adipocytes cultured at either 37°C or 31°C |
| Description | This study investigates how differentiated white adipocytes adapt to cooler temperatures by remodeling their acetyl-lysine–modified proteome. Differentiated adipocytes were cultured at 37°C or 31°C for 12 days to induce temperature-dependent physiological and biochemical changes. To profile acetylation dynamics on a global scale, proteins were extracted, digested with trypsin, and subjected to immunoprecipitation (IP) of acetyl-lysine–modified peptides. The resulting enriched peptides were analyzed by mass spectrometry to identify and quantify acetylation sites, enabling comparison of acetylation patterns between cells cultured at 37°C and 31°C. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-09-07 |
| AnnouncementXML | Submission_2026-09-07_04:21:57.766.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Hiroyuki Mori |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | acetylated residue |
| Instrument | Orbitrap Fusion |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-06-08 20:21:12 | ID requested | |
| ⏵ 1 | 2026-09-07 04:21:58 | announced | |
Publication List
| 10.1096/fj.202601941r; |
| Mori H, Hariri H, Moe W, Durham S, Guzman Y, Paulsson E, Simmermon RC, Bhanderi PB, Peterson SK, Dickson MJ, Evans CR, MacDougald OA, Adaptation of White Adipocytes to Cooler Temperatures: Impacts on Energy Metabolism and Protein Acetylation. FASEB J, 40(15):e72164(2026) [pubmed] |
Keyword List
| submitter keyword: adipocytes cultured at either 37°C or 31°C,acetyl‑lysine proteomics |
Contact List
| Ormond A. MacDougald |
|---|
| contact affiliation | Department of Molecular & Integrative Physiology, University of Michigan Medical School, |
| contact email | macdouga@umich.edu |
| lab head | |
| Hiroyuki Mori |
|---|
| contact affiliation | University of Michigan |
| contact email | morimori@umich.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD079423 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD079423
- Label: PRIDE project
- Name: Adaptation of white adipocytes to cooler temperatures: adipocytes cultured at either 37°C or 31°C
