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PXD078962
PXD078962 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Lysine Acetylome Analysis Reveals the Critical Role of Acetylation-Modified Transcription Factors and a Chaperone Protein in Regulation of Salt Tolerance in Tamarix hispida |
| Description | Using 4D label-free quantitative acetylproteomics, we profiled the lysine acetylome of Tamarix hispida under 200 mM NaCl stress. We identified 7,557 lysine acetylation (Kac) sites on 3,136 proteins, of which 559 sites on 478 proteins were salt-responsive. KEGG enrichment analysis revealed that these proteins were primarily involved in pyruvate metabolism and carotenoid biosynthesis, suggesting that acetylation remodels central metabolic pathways during salt adaptation. Salt stress also increased acetylation of five histones and two histone acetyltransferases (KAT3 and NAT3), implicating epigenetic mechanisms. Among 24 acetylated proteins from six families of TFs and one non-TF target protein (HSP), HSPs and zinc-finger types were predominant. Mutation of Kac sites in four selected proteins (ThNAC68, ThCHCC, ThC3H, ThHSP70) abolished their salt-induced acetylation. Our work delineates the lysine acetylome of T. hispida under salt stress and establishes TF acetylation as a key regulatory layer in salt adaptation, offering new insights into post translational and epigenetic networks underlying stress tolerance in woody plants. |
| HostingRepository | iProX |
| AnnounceDate | 2026-05-28 |
| AnnouncementXML | Submission_2026-06-23_19:51:19.996.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Xin Xu |
| SpeciesList | scientific name: Tamarix hispida; NCBI TaxID: 189793; |
| ModificationList | acetylated residue |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-05-28 00:44:02 | ID requested | |
| ⏵ 1 | 2026-06-23 19:51:20 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Tamarix hispida, Lysine Acetylome, salt stress |
Contact List
| Xiaoyu Ji | |
|---|---|
| contact affiliation | Shenyang Agricultural University |
| contact email | jixiaoyu@syau.edu.cn |
| lab head | |
| Xin Xu | |
| contact affiliation | Shenyang Agricultural University |
| contact email | xuxin25813@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
