⮝ Full datasets listing
PXD078664
PXD078664 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | EndoTag AP-MS Profiling of Chromatin Modifier Interactome Rewiring in MDA-MB-468 Cells Upon Paclitaxel Perturbation |
| Description | This submission comprises affinity purification mass spectrometry (AP-MS) raw data generated from endogenously tagged MDA-MB-468 cells under Paclitaxel perturbation. The dataset focuses on drug-induced interactome rewiring of chromatin modifiers relevant to the triple-negative breast cancer context. All AP-MS experiments were performed in four biological replicates. Each AP-MS batch includes an untagged parental control, 10 chromatin modifier tagged cell lines, and a positive control tagged line. DMSO-treated samples serve as vehicle control across all AP-MS experiments (Unpublished data). |
| HostingRepository | MassIVE |
| AnnounceDate | 2026-05-21 |
| AnnouncementXML | Submission_2026-05-21_16:09:00.403.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Richa Tiwari |
| SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-05-21 01:17:17 | ID requested | |
| ⏵ 1 | 2026-05-21 16:09:00 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: Endotagging, AP-MS, Triple Negative Breast Cancer, MDA-MB-468, Paclitaxel, CM4AI, Bridge2AI, DatasetType:Proteomics |
Contact List
| Dr. Nevan J. Krogan | |
|---|---|
| contact affiliation | Department of Cellular and Molecular Pharmacology, University of California San Francisco, USA |
| contact email | nevan.krogan@ucsf.edu |
| lab head | |
| Richa Tiwari | |
| contact affiliation | UCSF |
| contact email | richa.tiwari@ucsf.edu |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v13/MSV000101915/ |
