⮝ Full datasets listing
PXD078594
PXD078594 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic Profiling of CSF and Serum in Recurrent High-Grade GBM Patients During CAR-T Therapy: Novel Biomarkers and Pathway Implications |
| Description | We prospectively collected 36 paired cerebrospinal fluid (CSF) and serum (SE) samples from 3 recurrent high-grade GBM patients (overall survival > 12 months) at baseline (Day 0) and on post-CAR-T treatment days 1-5. Comprehensive untargeted proteomic profiling was conducted using liquid chromatography-mass spectrometry (LC-MS). We characterized inter-sample proteomic variations through proteomic approaches, elucidated exploratory proteomic changes observed in patients receiving CAR-T therapy, and conducted systematic functional annotation. |
| HostingRepository | iProX |
| AnnounceDate | 2026-05-19 |
| AnnouncementXML | Submission_2026-05-20_00:58:59.371.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Zi Zhuang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | 4800 Plus MALDI TOF/TOF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-05-20 00:57:24 | ID requested | |
| ⏵ 1 | 2026-05-20 00:58:59 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Glioblastoma,CAR-T therapy,Untargeted mass spectrometry |
Contact List
| Lin Wang | |
|---|---|
| contact affiliation | The Fourth Affiliated Hospital of Soochow University |
| contact email | 248439206@qq.com |
| lab head | |
| Zi Zhuang | |
| contact affiliation | The Fourth Affiliated Hospital of Soochow University |
| contact email | 15855167157@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
