⮝ Full datasets listing
PXD078239
PXD078239 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Engineering lipid nanoparticle surface hydrophobicity to modulate nano-bio interface and enable tissue-selective mRNA delivery |
| Description | This dataset contains label-free quantitative proteomics data characterizing the plasma protein corona of dendrimer-based lipid nanoparticles (dLNPs) with varying surface hydrophobicity. dLNPs were incubated with mouse plasma (C57BL/6, K2 EDTA) ex vivo at 37 C for 15 min, and corona proteins were isolated by sucrose cushion centrifugation. Samples were digested with Trypsin/Lys-C and analyzed by nano-LC/MS/MS on a Thermo Q Exactive HF Orbitrap. Data were processed using PEAKS 12.5 against the Mus musculus UniProt database. |
| HostingRepository | MassIVE |
| AnnounceDate | 2026-05-11 |
| AnnouncementXML | Submission_2026-05-11_17:04:17.992.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Zijing Xu |
| SpeciesList | scientific name: Mus musculus; common name: house mouse; NCBI TaxID: 10090; |
| ModificationList | Carbamidomethyl; Oxidation |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-05-11 14:26:40 | ID requested | |
| ⏵ 1 | 2026-05-11 17:04:18 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: Lipid nanoparticles, Protein corona, Tissue selective mRNA delivery, DatasetType:Proteomics |
Contact List
| Fan Zhang, PhD | |
|---|---|
| contact affiliation | University of Florida |
| contact email | fzhang1@cop.ufl.edu |
| lab head | |
| Zijing Xu | |
| contact affiliation | University of Florida |
| contact email | zijingxu@ufl.edu |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v11/MSV000101798/ |
