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PXD078079

PXD078079 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic profiling of AML patient-derived xenografts across serial transplantation
DescriptionThis dataset contains mass spectrometry-based proteomic profiling of acute myeloid leukemia patient-derived xenograft samples collected across serial transplantation stages. The study aimed to characterize proteome remodeling associated with leukemia propagation and disease evolution in AML PDX models. Proteomic data were generated from xenografted human AML cells and are part of a broader multi-omics study integrating serial xenotransplantation, transcriptomics, proteomics and functional therapeutic analyses.
HostingRepositoryPRIDE
AnnounceDate2026-07-20
AnnouncementXMLSubmission_2026-07-19_22:29:39.603.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterjerome Tamburini
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-05-06 14:26:10ID requested
12026-07-19 22:29:40announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Acute myeloid leukemia
AML
patient-derived xenograft
PDX
serial transplantation
proteomics
mass spectrometry
leukemia stem cells
Contact List
Jerome Tamburini
contact affiliationTranslational Research Centre in Onco-hematology, Faculty of Medicine, University of Geneva, and Swiss Cancer Center Leman, Geneva, Switzerland
contact emailjerome.tamburinibonnefoy@unige.ch
lab head
jerome Tamburini
contact affiliationGeneva University
contact emailjerome.tamburinibonnefoy@unige.ch
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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