PXD077984

PXD077984 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Identification of the protein network associated with EGFP::ATG16L1 and ARHGAP15::MYC
Description	These datasets contain mass spectrometry-based proteomics results from affinity-purification/pulldown assays designed to identify proteins associated with the autophagy regulator EGFP::ATG16L1 and the RAC1-specific GTPase-activating protein ARHGAP15::MYC. Experiments were performed using mouse embryonic fibroblasts expressing tagged EGFP::ATG16L1 or ARHGAP15::MYC, followed by immunoprecipitation using GFP-Trap or Myc-Trap/anti-tag magnetic agarose beads and LC–MS/MS analysis. The datasets were generated to investigate protein interaction networks linking ARHGAP15, RAC1 signalling, ATG16L1-dependent autophagy and centrosome regulation.
HostingRepository	PRIDE
AnnounceDate	2026-06-18
AnnouncementXML	Submission_2026-06-18_01:01:37.844.xml
DigitalObjectIdentifier	https://doi.org/10.6019/PXD077984
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Agata Malinowska
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationList	methylthiolated residue; monohydroxylated residue
Instrument	Orbitrap Exploris 480

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2026-05-04 11:21:00	ID requested
⏵ 1	2026-06-18 01:01:38	announced

Publication List

10.6019/PXD077984;

10.6019/PXD077984;

Keyword List

submitter keyword: ATG16L1
ARHGAP15
RAC1
autophagy
centrosomes
mouse embryonic fibroblasts
pulldown
mass spectrometry

submitter keyword: ATG16L1

ARHGAP15

RAC1

autophagy

centrosomes

mouse embryonic fibroblasts

pulldown

mass spectrometry

Contact List

Prof. David M. Glover
contact affiliation	Biology and Biological Engineering Division, California Institute of Technology, USA
contact email	dmglover@caltech.edu
lab head
Agata Malinowska
contact affiliation	IBB PAS
contact email	esme@ibb.waw.pl
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD077984
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD077984

PRIDE project URI

Repository Record List

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