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PXD077551

PXD077551 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic profiling of proteasome inhibitor-resistant multiple myeloma cells
DescriptionAcquired resistance to proteasome inhibitors remains a major therapeutic challenge in multiple myeloma. In this study, we investigated mechanisms underlying resistance to bortezomib and carfilzomib using comprehensive proteomic profiling of RPMI8226 and U266B1 cell lines across different stages of resistance evolution.
HostingRepositoryiProX
AnnounceDate2026-04-24
AnnouncementXMLSubmission_2026-04-23_18:49:59.752.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMagdalena Luczak
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListacetylated residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-04-23 18:48:54ID requested
12026-04-23 18:50:00announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: multiple myeloma, proteasome inhibitors, resistance
Contact List
Magdalena Luczak
contact affiliationInstitute of Bioorganic Chemistry Polish Academy of Sciences
contact emailmagdalu@ibch.poznan.pl
lab head
Magdalena Luczak
contact affiliationInstitute of Bioorganic Chemistry Polish Academy of Sciences
contact emailmagdalu@ibch.poznan.pl
dataset submitter
Full Dataset Link List
iProX dataset URI