PXD077506

PXD077506 is an original dataset announced via ProteomeXchange.

Title	ntegrated Analysis of Gut Microbiota, Serum Metabolomics, and Proteomics Reveals Novel Associations With Clinical Symptoms in Patients With Cerebral Infarction
Description	A total of 20 CI patients and 20 healthy controls (HC) were enrolled. Fecal microbiota was profiled using 16S rRNA gene high-throughput sequencing. Serum metabolomics and proteomics were analyzed using ultra-high-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) and data-independent acquisition (DIA) proteomics, respectively. Spearman correlation and multi-omics integration were applied to explore the associations among microbiota, metabolites, proteins, and clinical indicators.
HostingRepository	iProX
AnnounceDate	2026-04-23
AnnouncementXML	Submission_2026-04-22_20:38:53.289.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Xingbang Wang
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Astral

Revision	Datetime	Status	ChangeLog Entry
0	2026-04-22 20:38:15	ID requested
⏵ 1	2026-04-22 20:38:53	announced

Dataset with its publication pending

submitter keyword: cerebral infarction, gut microbiota, metabolomics, proteomics, multi-omics integration

gut–brain axis, inflammation

Xingbang Wang
contact affiliation	Qiluhospital of Shandong University
contact email	wangxingbang@qiluhospital.cn
lab head
Xingbang Wang
contact affiliation	Qiluhospital of Shandong University
contact email	wangxingbang@qiluhospital.cn
dataset submitter

iProX dataset URI