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PXD077347

PXD077347 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleH3pT11 regulates histone homeostasis and replication-coupled nucleosome assembly
Descriptionnewly synthesized H3 is phosphorylated at T11 by the CPC complex, licensing Asf1 binding and nuclear import; upon nuclear entry, H3pT11 facilitates Rtt109-catalyzed H3K56 acetylation, which antagonizes Hat1 and promotes nucleosome assembly by CAF-1 and Rtt106 16; subsequently, Rtt101-mediated H3K122 ubiquitination destabilizes the Asf1-H3/H4 interaction, enabling dimer transfer from Asf1 to CAF-1
HostingRepositoryPRIDE
AnnounceDate2026-08-05
AnnouncementXMLSubmission_2026-08-04_22:39:39.375.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYu Qi
SpeciesList scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: NEWT:4932;
ModificationListphosphorylated residue; acetylated residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-04-19 09:51:34ID requested
12026-08-04 22:39:39announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: H3K79me3 H3T11 phosphorylation histone homeostasis
Contact List
Yu qi
contact affiliationSchool of Life Sciences, Hubei University, Wuhan, Hubei 430062, China
contact emailyuqi195316@outlook.com
lab head
Yu Qi
contact affiliationhubei university
contact emailyuqi195316@outlook.com
dataset submitter
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Dataset FTP location
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PRIDE project URI
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