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PXD076770

PXD076770 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDe novo sequencing of monoclonal immunoglobulin light chains associated with LCPT
DescriptionThis project provides high-resolution LC-MS/MS datasets dedicated to the de novo sequencing of monoclonal immunoglobulin light chains (FLCs) associated with light chain proximal tubulopathy (LCPT). LCPT is a rare renal manifestation of plasma cell dyscrasias, characterized by proximal tubule dysfunction. The disease encompasses both crystalline and non-crystalline variants: while the former is defined by the formation of organized intracellular crystals, the latter presents as tubular dysfunction in the absence of observable inclusions.
HostingRepositoryiProX
AnnounceDate2026-04-09
AnnouncementXMLSubmission_2026-06-08_18:02:44.017.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterXin Wang
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Eclipse
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-04-08 20:32:28ID requested
12026-06-08 18:02:44announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: immunoglobulin light chains, LCPT, de novo sequencing
Contact List
Minghui Zhao
contact affiliationPeking University
contact emailmhzhao@bjmu.edu.cn
lab head
Xin Wang
contact affiliationPeking University
contact emailwangxin_sh@foxmail.com
dataset submitter
Full Dataset Link List
iProX dataset URI