⮝ Full datasets listing
PXD076650
PXD076650 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Based on multi-omics, revealing the key role of MOESIN lactic acidification-driven TGF-β signaling axis in improving diabetic osteoporosis through gut microbiota |
| Description | Diabetic osteoporosis (DOP), as a typical representative of metabolic-immune cross-talk imbalance, has an unclear pathogenesis and lacks effective targeted intervention methods. This study aims to systematically analyze the molecular mechanism by which fecal microbiota transplantation (FMT) activates the TGF-β signaling axis through MOESIN lactic acid modification, reshapes the Treg/Th17 immune balance, and improves the pathological process of DOP based on multi-omics integrated analysis |
| HostingRepository | iProX |
| AnnounceDate | 2026-04-03 |
| AnnouncementXML | Submission_2026-04-07_01:02:10.862.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Hong Li |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | X500R QTOF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-04-07 01:01:26 | ID requested | |
| ⏵ 1 | 2026-04-07 01:02:11 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Intestinal flora transplantation |
Contact List
| Jiajia Lu | |
|---|---|
| contact affiliation | Shanghai Changzheng Hospital |
| contact email | lujiajia@smmu.edu.cn |
| lab head | |
| Hong Li | |
| contact affiliation | Shanghai Changzheng Hospital |
| contact email | 2194835461@qq.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
