PXD076520 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | qChIP-MS reveals the local chromatin composition by label-free quantitative proteomics |
| Description | Chromatin immunoprecipitation (ChIP) has been a cornerstone for epigenetic analyses over the last decades, but even coupled to sequencing approaches (ChIP-seq), it is ultimately limited to one protein at a time. In a complementary effort, we here combine ChIP with label-free quantitative mass spectrometry (qChIP-MS) to interrogate local chromatin compositions. We demonstrate the versatility of our approach at telomeres, with transcription factors, in tissue and by dCas9-mediated locus-specific enrichment. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-04-03 |
| AnnouncementXML | Submission_2026-04-02_20:12:00.886.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Dennis Kappei |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF; timsTOF fleX |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-04-02 11:00:58 | ID requested | |
| ⏵ 1 | 2026-04-02 20:12:01 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
Contact List
| Dennis Kappei |
|---|
| contact affiliation | Cancer Science Institute of Singapore (CSI), National University of Singapore (NUS) |
| contact email | dennis.kappei@nus.edu.sg |
| lab head | |
| Dennis Kappei |
|---|
| contact affiliation | Cancer Science Institute of Singapore |
| contact email | dennis.kappei@nus.edu.sg |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD076520 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD076520
- Label: PRIDE project
- Name: qChIP-MS reveals the local chromatin composition by label-free quantitative proteomics
