PXD076431 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Antifungal turbinmicin alters functional vesicle cargo |
| Description | Extracellular vesicle delivery in Candida biofilms is important for matrix delivery and associated drug-resistance. Prior study found the antifungal turbinmicin inhibits vesicle release. We find the antifungal turbinmicin inhibits both vesicle release as well as cargo loading. Using comparative vesicle proteome analysis in turbinmicin treated biofilms we identify several components blocked from cargo loading that play specific roles in the functional matrix protection mechanism. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-04-06 |
| AnnouncementXML | Submission_2026-04-06_06:50:29.288.xml |
| DigitalObjectIdentifier | https://doi.org/10.6019/PXD076431 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Greg Sabat |
| SpeciesList | scientific name: Candida albicans (Yeast); NCBI TaxID: NEWT:5476; |
| ModificationList | monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-03-31 19:31:06 | ID requested | |
| ⏵ 1 | 2026-04-06 06:50:29 | announced | |
Publication List
Keyword List
| submitter keyword: turbinmicin, proteomics,Candida, extracellular vesicles |
Contact List
| Dr. David R. Andes |
|---|
| contact affiliation | Department of Medicine, University of Wisconsin - Madison |
| contact email | dra@medicine.wisc.edu |
| lab head | |
| Greg Sabat |
|---|
| contact affiliation | University of Wisconsin |
| contact email | gsabat@wisc.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD076431
- Label: PRIDE project
- Name: Antifungal turbinmicin alters functional vesicle cargo
