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PXD076182

PXD076182 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleManganese enhances macrophage bactericidal activity by repressing Sirt3 for Staphylococcus aureus osteomyelitis treatment
DescriptionPrimary mouse BMDMs were cultured in vitro and divided into three groups: uninfected (blank), S. aureus-infected (control), and S. aureus-infected with Mn²⁺ treatment (Mn²⁺). A total of 9 samples were analyzed (n = 3 per group). The blank group received no treatment, the control group was stimulated with S. aureus for 12 h, and the Mn²⁺ group was pretreated with 100 μM Mn²⁺ for 12 h before S. aureus stimulation for 12 h in the continued presence of 100 μM Mn²⁺.
HostingRepositoryiProX
AnnounceDate2026-03-26
AnnouncementXMLSubmission_2026-03-26_01:20:49.831.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterBowen Bai
SpeciesList scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Astral
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-03-26 01:20:03ID requested
12026-03-26 01:20:50announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: S. aureus-induced osteomyelitis, manganese, macrophage
Contact List
Bowei Wang
contact affiliationSouthern Medical University
contact emailhellobowei@hotmail.com
lab head
Bowen Bai
contact affiliationSouthern Medical University
contact email1125776556@qq.com
dataset submitter
Full Dataset Link List
iProX dataset URI