⮝ Full datasets listing
PXD075843
PXD075843 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Protein Expression Profiling in Placental Tissues of Preeclampsia Patients |
| Description | Abnormal syncytialization of cytotrophoblast (CTB) cells is known to be associated with preeclampsia (PE), yet its underlying molecular mechanisms remain elusive. In this study, proteomic analysis of placental tissues was performed to identify PE-related pathogenic genes. The results showed that NCK Adaptor Protein 1 (NCK1) was downregulated in placental tissues from patients with early-onset PE. Our work suggested that NCK1 is a potential therapeutic target for PE. |
| HostingRepository | iProX |
| AnnounceDate | 2026-03-19 |
| AnnouncementXML | Submission_2026-05-20_01:44:24.335.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yingying Hao |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-03-19 00:50:25 | ID requested | |
| ⏵ 1 | 2026-05-20 01:44:24 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: NCK1, preeclampsia, proteomic analysis |
Contact List
| Yingying Hao | |
|---|---|
| contact affiliation | Shengjing Hospital of China Medical University |
| contact email | haoyy_doc@163.com |
| lab head | |
| Yingying Hao | |
| contact affiliation | Shengjing Hospital of China Medical University |
| contact email | haoyy_doc@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
