PXD075835

PXD075835 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Mapping ISG15 sites in HeLa cells during MPXV virus infection
Description	We applied an ISG15-GlyGly peptidomics approach to HeLa cells infected with monkeypox virus (MPXV). Cells were lysed in 5% SDS and processed using S-Trap columns. Following trypsin digestion, GlyGly-modified peptides were enriched and subsequently identified and quantified by LC–MS/MS. In addition, a shotgun proteomics analysis was performed on the same samples prior to GlyGly-enrichment.
HostingRepository	PRIDE
AnnounceDate	2026-09-01
AnnouncementXML	Submission_2026-09-01_02:37:18.659.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Denzel Eggermont
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; scientific name: Monkeypox virus; NCBI TaxID: NEWT:10244;
ModificationList	ubiquitination signature dipeptidyl lysine; iodoacetamide derivatized residue
Instrument	Q Exactive HF; orbitrap instrument

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2026-03-18 21:33:00	ID requested
⏵ 1	2026-09-01 02:37:19	announced

Publication List

10.1038/S42003-026-10867-9;

10.1038/S42003-026-10867-9;

Keyword List

submitter keyword: MPXV, HeLa,ISG15

submitter keyword: MPXV, HeLa,ISG15

Contact List

Francis Impens
contact affiliation	VIB-UGent Center for Medical Biotechnology, VIB, Ghent, Belgium
contact email	francis.impens@vib-ugent.be
lab head
Denzel Eggermont
contact affiliation	VIB-Ugent Center for Medical Biotechnology
contact email	denzel.eggermont@vib-ugent.be
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD075835
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD075835

PRIDE project URI

Repository Record List

[ + ]