⮝ Full datasets listing
PXD075827
PXD075827 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Laminar shear stress inhibits endothelial-mesenchymal transition and improves atherosclerosis through SRXN1 |
| Description | Atherosclerosis (AS) is one of the main causes of cardiovascular diseases, and its complex pathophysiological mechanism involves the interaction of multiple factors. Laminar shear stress (LSS) plays a key role in the regulation of AS processes, but its specific mechanism is still unclear. In this study, we analyzed the proteome data of static culture and LSS-treated human aortic endothelial cells (HAECs), to explore the role and potential mechanism of LSS in AS. |
| HostingRepository | iProX |
| AnnounceDate | 2026-03-19 |
| AnnouncementXML | Submission_2026-03-18_20:24:25.730.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Xingyu Jiang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-03-18 20:23:47 | ID requested | |
| ⏵ 1 | 2026-03-18 20:24:26 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Atherosclerosis, Laminar shear stress, SRXN1, EndMT, Endothelial cells |
Contact List
| Bin Liu | |
|---|---|
| contact affiliation | Jilin University |
| contact email | binliu@jlu.edu.cn |
| lab head | |
| Xingyu Jiang | |
| contact affiliation | Jilin University |
| contact email | xingyuj23@jlu.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
