⮝ Full datasets listing
PXD075786
PXD075786 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic signatures induced by KRAS secondary mutation in AsPC1 cells |
| Description | In this study, we performed a proteomic analysis to characterize differences in protein expression between KRASG12D secondary-mutant cell lines and KRASG12D single-mutant cell lines. Through systematic data analysis, we identified the key signaling pathways and regulatory proteins associated with resistance to KRASG12D inhibitors, and further explored combination therapeutic strategies to overcome drug resistance. |
| HostingRepository | iProX |
| AnnounceDate | 2026-03-18 |
| AnnouncementXML | Submission_2026-03-17_20:41:31.547.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Xianglei Zhang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-03-17 20:41:00 | ID requested | |
| ⏵ 1 | 2026-03-17 20:41:32 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: KRAS secondary mutation |
Contact List
| Fang Bai | |
|---|---|
| contact affiliation | ShanghaiTech University |
| contact email | baifang@shanghaitech.edu.cn |
| lab head | |
| Xianglei Zhang | |
| contact affiliation | ShanghaiTech University |
| contact email | zhxilvaff@126.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
