⮝ Full datasets listing
PXD075474
PXD075474 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic signatures in chondrosarcoma and chondrocytes after proton irradiation |
| Description | In this project, we conducted a comprehensive analysis of the effects of proton irradiation on normal chondrocytes (MC615) and CHS cells (SW1353), focusing on survival capacity, genotoxic burden, oxidative stress dynamics, cell cycle alterations, and proteomic remodeling that further investigates the physical properties of protons and their cellular impact. By delineating the divergent biological responses between normal and malignant cartilage cells, we aimed to identify potential therapeutic targets that could enhance the efficacy of proton therapy while minimizing damage to healthy tissues. |
| HostingRepository | iProX |
| AnnounceDate | 2026-03-10 |
| AnnouncementXML | Submission_2026-03-10_19:08:59.897.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Benoit Bernay |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | LTQ |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-03-10 19:08:43 | ID requested | |
| ⏵ 1 | 2026-03-10 19:09:00 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: proton irradiation |
| chondrosarcoma |
Contact List
| Diana Savu | |
|---|---|
| contact affiliation | Horia Hulubei National Institute of Physics and Nuclear Engineering - IFIN-HH |
| contact email | chevalier@ganil.fr |
| lab head | |
| Benoit Bernay | |
| contact affiliation | Université de Caen, US EMerode, Plateforme Proteogen |
| contact email | benoit.bernay@unicaen.fr |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
